Tubulin/VEGFR-2-IN-2, CAS [[2882998-56-1]] Preis auf Anfrage

Produktübersicht

• Artikelname: Tubulin/VEGFR-2-IN-2, CAS [[2882998-56-1]] Preis auf Anfrage
• Artikelnummer: MCE-HY-180292
• Hersteller Artikelnummer: HY-180292
• Alternativnummer: MCE-HY-180292-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

Tubulin/VEGFR-2-IN-2 is an orally active tubulin and VEGFR-2 inhibitor with IC50s of 3.27 and 0.09 µM, respectively. Tubulin/VEGFR-2-IN-2 exerts the antitumor effects through multifaceted pathways, including enhancing reactive oxygen species (ROS) generation, disrupting mitochondrial membrane potential, inducing apoptosis, and arresting the cell cycle. Tubulin/VEGFR-2-IN-2 demonstrates anti-angiogenic properties by significantly impairing endothelial cell migration, invasion, and tube formation in vitro. Tubulin/VEGFR-2-IN-2 suppresses angiogenesis, tumor growth, and metastasis in vivo. Tubulin/VEGFR-2-IN-2 can be used for non-small lung cancer, breast cancer, gastric cancer and lymphoma[1].

Produkteigenschaften

• Molekulargewicht: 366.41
• CAS Nummer: [2882998-56-1]
• Formel: C20H22N4O3
• Target-Kategorie: Apoptosis,Microtubule/Tubulin,Reactive Oxygen Species (ROS),VEGFR

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound