Tubulin/VEGFR-2-IN-2, CAS [[2882998-56-1]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-180292
Supplier Catalog Number:
HY-180292
Alternative Catalog Number:
MCE-HY-180292-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Tubulin/VEGFR-2-IN-2 is an orally active tubulin and VEGFR-2 inhibitor with IC50s of 3.27 and 0.09 µM, respectively. Tubulin/VEGFR-2-IN-2 exerts the antitumor effects through multifaceted pathways, including enhancing reactive oxygen species (ROS) generation, disrupting mitochondrial membrane potential, inducing apoptosis, and arresting the cell cycle. Tubulin/VEGFR-2-IN-2 demonstrates anti-angiogenic properties by significantly impairing endothelial cell migration, invasion, and tube formation in vitro. Tubulin/VEGFR-2-IN-2 suppresses angiogenesis, tumor growth, and metastasis in vivo. Tubulin/VEGFR-2-IN-2 can be used for non-small lung cancer, breast cancer, gastric cancer and lymphoma[1].
Molecular Weight:
366.41
CAS Number:
[2882998-56-1]
Formula:
C20H22N4O3
Target:
Apoptosis,Microtubule/Tubulin,Reactive Oxygen Species (ROS),VEGFR
Application Notes:
MCE Product type: Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted
