ER-38925 is a retinoid agonist with selevtivity to retinoic acid receptor subtype alpha (RAR-alpha). ER-38925 prolongs the lifespan of the recipient mice dose-dependently. ER-38925 potently inhibits alloantigenstimulated donor T lymphocyte prolifertion in vitro. ER-38925 can prevent the development of antiallogeneic cytotoxic T lymphocyte response in mice. ER-38925 inhibits serum anti-DNA autoantibody production in mouse model of human chronic GVHD[1].
Molekulargewicht:
331.37
CAS Nummer:
[196517-43-8]
Formel:
C21H17NO3
Target-Kategorie:
RAR/RXR
Anwendungsbeschreibung:
MCE Product type: Reference compound
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