ER-38925 is a retinoid agonist with selevtivity to retinoic acid receptor subtype alpha (RAR-alpha). ER-38925 prolongs the lifespan of the recipient mice dose-dependently. ER-38925 potently inhibits alloantigenstimulated donor T lymphocyte prolifertion in vitro. ER-38925 can prevent the development of antiallogeneic cytotoxic T lymphocyte response in mice. ER-38925 inhibits serum anti-DNA autoantibody production in mouse model of human chronic GVHD[1].
Molecular Weight:
331.37
CAS Number:
[196517-43-8]
Formula:
C21H17NO3
Target:
RAR/RXR
Application Notes:
MCE Product type: Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted
