Nurr1/RXR agonist 1, CAS [[2231746-53-3]] Preis auf Anfrage

Produktübersicht

• Artikelname: Nurr1/RXR agonist 1, CAS [[2231746-53-3]] Preis auf Anfrage
• Artikelnummer: MCE-HY-180576
• Hersteller Artikelnummer: HY-180576
• Alternativnummer: MCE-HY-180576-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

Nurr1/RXR dual agonist 1 is a dual activator of Nurr1 (EC50 = 2.6 µM) and RXR with K[1]s of 0.6 and 1.1 µM, respectively. Nurr1/RXR dual agonist 1 exclusively activates the heterodimer response element DR5 by selectively destabilizing the Nurr1 homodimer and stabilizing the Nurr1:RXR heterodimer. Nurr1/RXR dual agonist 1 enhances expression of a specific subset of neuroprotective Nurr1 target genes while avoiding induction of genes associated with potential off-target effects in neuronal cells. Nurr1/RXR dual agonist 1 can be used for neurodegenerative diseases research[1].

Produkteigenschaften

• Molekulargewicht: 319.35
• CAS Nummer: [2231746-53-3]
• Formel: C18H19F2NO2
• Target-Kategorie: Nuclear Hormone Receptor 4A/NR4A,RAR/RXR

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound