Nurr1/RXR agonist 1, CAS [[2231746-53-3]] Preis auf Anfrage

Product Overview

• Article Name: Nurr1/RXR agonist 1, CAS [[2231746-53-3]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-180576
• Supplier Catalog Number: HY-180576
• Alternative Catalog Number: MCE-HY-180576-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

Nurr1/RXR dual agonist 1 is a dual activator of Nurr1 (EC50 = 2.6 µM) and RXR with K[1]s of 0.6 and 1.1 µM, respectively. Nurr1/RXR dual agonist 1 exclusively activates the heterodimer response element DR5 by selectively destabilizing the Nurr1 homodimer and stabilizing the Nurr1:RXR heterodimer. Nurr1/RXR dual agonist 1 enhances expression of a specific subset of neuroprotective Nurr1 target genes while avoiding induction of genes associated with potential off-target effects in neuronal cells. Nurr1/RXR dual agonist 1 can be used for neurodegenerative diseases research[1].

Product Properties

• Molecular Weight: 319.35
• CAS Number: [2231746-53-3]
• Formula: C18H19F2NO2
• Target: Nuclear Hormone Receptor 4A/NR4A,RAR/RXR

Application Notes

• Application Notes: MCE Product type: Reference compound