IRAK4-IN-33, CAS [[2411497-72-6]] Preis auf Anfrage

Artikelnummer: MCE-HY-180579
Artikelname: IRAK4-IN-33, CAS [[2411497-72-6]] Preis auf Anfrage
Artikelnummer: MCE-HY-180579
Hersteller Artikelnummer: HY-180579
Alternativnummer: MCE-HY-180579-1UNIT
Hersteller: MedchemExpress
Kategorie: Biochemikalien
IRAK4-IN-33 (Compound 22) is a selective, potent and orally active interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor with an IC50 0.36 nM. IRAK4-IN-33 can block the pro-inflammatory signaling pathway mediated by IRAK4 and inhibit the release of TNFalpha and IFNalpha. IRAK4-IN-33 shows weak inhibition for hERG channel (IC50 > 30 µM). IRAK4-IN-33 can be used for the research of inflammation and immunology, such as rheumatoid arthritis[1].
Molekulargewicht: 538.63
CAS Nummer: [2411497-72-6]
Formel: C27H26N10OS
Target-Kategorie: IFNAR,IRAK,TNF Receptor
Anwendungsbeschreibung: MCE Product type: Reference compound