IRAK4-IN-33, CAS [[2411497-72-6]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-180579
Supplier Catalog Number:
HY-180579
Alternative Catalog Number:
MCE-HY-180579-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
IRAK4-IN-33 (Compound 22) is a selective, potent and orally active interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor with an IC50 0.36 nM. IRAK4-IN-33 can block the pro-inflammatory signaling pathway mediated by IRAK4 and inhibit the release of TNFalpha and IFNalpha. IRAK4-IN-33 shows weak inhibition for hERG channel (IC50 > 30 µM). IRAK4-IN-33 can be used for the research of inflammation and immunology, such as rheumatoid arthritis[1].
Molecular Weight:
538.63
CAS Number:
[2411497-72-6]
Formula:
C27H26N10OS
Target:
IFNAR,IRAK,TNF Receptor
Application Notes:
MCE Product type: Reference compound
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