Azithromycin-amide-C3-amide-quinoxaline Preis auf Anfrage

Artikelnummer: MCE-HY-180767
Artikelname: Azithromycin-amide-C3-amide-quinoxaline Preis auf Anfrage
Artikelnummer: MCE-HY-180767
Hersteller Artikelnummer: HY-180767
Alternativnummer: MCE-HY-180767-1UNIT
Hersteller: MedchemExpress
Kategorie: Biochemikalien
Azithromycin-amide-C3-amide-quinoxaline (Compound 5f) is an Azithromycin (HY-17506) derivative and antibacterial agent. Azithromycin-amide-C3-amide-quinoxaline inhibits topoisoisomerase I with an IC50 of 120.7 µM. Azithromycin-amide-C3-amide-quinoxaline interacts with 70S E. coli ribosome with a Kd of 0.8 nM. Azithromycin-amide-C3-amide-quinoxaline inhibits bacterial translation with an IC50 of 0.7 µM. Azithromycin-amide-C3-amide-quinoxaline shows antibacterial potency against S. pneumonia ATCC 49619, S. aureus ATCC 29213, E. faecalis ATCC 29212 with MICs of 0.06 µg/mL, 2 µg/mL, 0.5 µg/mL, respectively. Azithromycin-amide-C3-amide-quinoxaline exhibits anticancer activity against prostate cancer, colon cancer[1].
Molekulargewicht: 1005.24
Formel: C51H84N6O14
Target-Kategorie: Bacterial,Drug Derivative,Topoisomerase
Anwendungsbeschreibung: MCE Product type: Reference compound