Azithromycin-amide-C3-amide-quinoxaline Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-180767
Supplier Catalog Number:
HY-180767
Alternative Catalog Number:
MCE-HY-180767-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Azithromycin-amide-C3-amide-quinoxaline (Compound 5f) is an Azithromycin (HY-17506) derivative and antibacterial agent. Azithromycin-amide-C3-amide-quinoxaline inhibits topoisoisomerase I with an IC50 of 120.7 µM. Azithromycin-amide-C3-amide-quinoxaline interacts with 70S E. coli ribosome with a Kd of 0.8 nM. Azithromycin-amide-C3-amide-quinoxaline inhibits bacterial translation with an IC50 of 0.7 µM. Azithromycin-amide-C3-amide-quinoxaline shows antibacterial potency against S. pneumonia ATCC 49619, S. aureus ATCC 29213, E. faecalis ATCC 29212 with MICs of 0.06 µg/mL, 2 µg/mL, 0.5 µg/mL, respectively. Azithromycin-amide-C3-amide-quinoxaline exhibits anticancer activity against prostate cancer, colon cancer[1].
Molecular Weight:
1005.24
Formula:
C51H84N6O14
Target:
Bacterial,Drug Derivative,Topoisomerase
Application Notes:
MCE Product type: Reference compound
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