CDK2-IN-55, CAS [[3099101-44-4]] Preis auf Anfrage
Artikelnummer:
MCE-HY-180817
Hersteller Artikelnummer:
HY-180817
Alternativnummer:
MCE-HY-180817-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
CDK2-IN-55 (Compound 12c) is a CDK2 inhibitor with an IC50 value of 4.7 nM. CDK2-IN-55 also has a strong inhibitory effect on CDK1 (IC50 = 26.3 nM), moderate inhibitory effects on Aurora A (IC50 = 92.0 nM) and CDK9 (IC50 = 288 nM), and very weak inhibitory activities on CDK4, CDK6, DYRK1A, and GSK3beta (IC50 > 1000 nM). CDK2-IN-55 shows strong anti-proliferative activity against various cancer cell lines, inducing cell cycle arrest and apoptosis. CDK2-IN-55 can be used for research on colorectal cancer, lung cancer, and cervical cancer[1].
Molekulargewicht:
416.52
CAS Nummer:
[3099101-44-4]
Formel:
C18H20N6O2S2
Target-Kategorie:
Apoptosis,Aurora Kinase,CDK
Anwendungsbeschreibung:
MCE Product type: Reference compound
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