CDK2-IN-55, CAS [[3099101-44-4]] Preis auf Anfrage

Product Overview

• Article Name: CDK2-IN-55, CAS [[3099101-44-4]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-180817
• Supplier Catalog Number: HY-180817
• Alternative Catalog Number: MCE-HY-180817-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

CDK2-IN-55 (Compound 12c) is a CDK2 inhibitor with an IC50 value of 4.7 nM. CDK2-IN-55 also has a strong inhibitory effect on CDK1 (IC50 = 26.3 nM), moderate inhibitory effects on Aurora A (IC50 = 92.0 nM) and CDK9 (IC50 = 288 nM), and very weak inhibitory activities on CDK4, CDK6, DYRK1A, and GSK3beta (IC50 > 1000 nM). CDK2-IN-55 shows strong anti-proliferative activity against various cancer cell lines, inducing cell cycle arrest and apoptosis. CDK2-IN-55 can be used for research on colorectal cancer, lung cancer, and cervical cancer[1].

Product Properties

• Molecular Weight: 416.52
• CAS Number: [3099101-44-4]
• Formula: C18H20N6O2S2
• Target: Apoptosis,Aurora Kinase,CDK

Application Notes

• Application Notes: MCE Product type: Reference compound