HDAC6-IN-71, CAS [[3062867-16-4]] Preis auf Anfrage

Produktübersicht

• Artikelname: HDAC6-IN-71, CAS [[3062867-16-4]] Preis auf Anfrage
• Artikelnummer: MCE-HY-180829
• Hersteller Artikelnummer: HY-180829
• Alternativnummer: MCE-HY-180829-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

HDAC6-IN-71 (Compound 24) is a HDAC6 inhibitor with IC50 values for HDAC6 and HDAC1 of 13.68 and 443.12 nM respectively. HDAC6-IN-71 effectively inhibits the production of NO by mouse macrophages, with its IC50 being 2.31 µM. HDAC6-IN-71 inhibits the HDAC6-NF-kappaB signaling pathway, reduces the levels of phosphorylated IkappaB-alpha and IKK-alpha/beta, and suppresses the expression of downstream inflammatory proteins COX-2 and iNOS. HDAC6-IN-71 significantly alleviates ulcerative colitis in mice[1].

Produkteigenschaften

• Molekulargewicht: 323.30
• CAS Nummer: [3062867-16-4]
• Formel: C18H13NO5
• Target-Kategorie: COX,HDAC,IKK,NF-kappaB,NO Synthase

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound