HDAC6-IN-71, CAS [[3062867-16-4]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-180829
Supplier Catalog Number:
HY-180829
Alternative Catalog Number:
MCE-HY-180829-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
HDAC6-IN-71 (Compound 24) is a HDAC6 inhibitor with IC50 values for HDAC6 and HDAC1 of 13.68 and 443.12 nM respectively. HDAC6-IN-71 effectively inhibits the production of NO by mouse macrophages, with its IC50 being 2.31 µM. HDAC6-IN-71 inhibits the HDAC6-NF-kappaB signaling pathway, reduces the levels of phosphorylated IkappaB-alpha and IKK-alpha/beta, and suppresses the expression of downstream inflammatory proteins COX-2 and iNOS. HDAC6-IN-71 significantly alleviates ulcerative colitis in mice[1].
Molecular Weight:
323.30
CAS Number:
[3062867-16-4]
Formula:
C18H13NO5
Target:
COX,HDAC,IKK,NF-kappaB,NO Synthase
Application Notes:
MCE Product type: Reference compound
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