EGFR kinase-IN-8, CAS [[3081622-35-4]] Preis auf Anfrage
Artikelnummer:
MCE-HY-180922
| Artikelname: |
EGFR kinase-IN-8, CAS [[3081622-35-4]] Preis auf Anfrage |
| Artikelnummer: |
MCE-HY-180922 |
| Hersteller Artikelnummer: |
HY-180922 |
| Alternativnummer: |
MCE-HY-180922-1UNIT |
| Hersteller: |
MedchemExpress |
| Kategorie: |
Biochemikalien |
| EGFR kinase-IN-8 (Compound H8b) is an EGFR inhibitor. EGFR kinase-IN-8 potently inhibits both triple-mutated EGFRL858R/T790M/C797S (IC50 = 3.86 nM) and double-mutated EGFRL858R/T790M (IC50 = 1.23 nM). EGFR kinase-IN-8 suppresses EGFR phosphorylation and downstream AKT, STAT3, and MAPK signaling. EGFR kinase-IN-8 exhibits anticancer activity against non-small cell lung cancer[1]. |
| Molekulargewicht: |
710.03 |
| CAS Nummer: |
[3081622-35-4] |
| Formel: |
C31H40Cl3N8O3P |
| Target-Kategorie: |
Akt,EGFR,p38 MAPK,STAT |
| Anwendungsbeschreibung: |
MCE Product type: Reference compound |
