EGFR kinase-IN-8, CAS [[3081622-35-4]] Preis auf Anfrage
Catalog Number:
MCE-HY-180922
| Article Name: |
EGFR kinase-IN-8, CAS [[3081622-35-4]] Preis auf Anfrage |
| Biozol Catalog Number: |
MCE-HY-180922 |
| Supplier Catalog Number: |
HY-180922 |
| Alternative Catalog Number: |
MCE-HY-180922-1UNIT |
| Manufacturer: |
MedchemExpress |
| Category: |
Biochemikalien |
| EGFR kinase-IN-8 (Compound H8b) is an EGFR inhibitor. EGFR kinase-IN-8 potently inhibits both triple-mutated EGFRL858R/T790M/C797S (IC50 = 3.86 nM) and double-mutated EGFRL858R/T790M (IC50 = 1.23 nM). EGFR kinase-IN-8 suppresses EGFR phosphorylation and downstream AKT, STAT3, and MAPK signaling. EGFR kinase-IN-8 exhibits anticancer activity against non-small cell lung cancer[1]. |
| Molecular Weight: |
710.03 |
| CAS Number: |
[3081622-35-4] |
| Formula: |
C31H40Cl3N8O3P |
| Target: |
Akt,EGFR,p38 MAPK,STAT |
| Application Notes: |
MCE Product type: Reference compound |
