PDE3/4-IN-4, CAS [[3088024-27-2]] Preis auf Anfrage

Produktübersicht

• Artikelname: PDE3/4-IN-4, CAS [[3088024-27-2]] Preis auf Anfrage
• Artikelnummer: MCE-HY-181088
• Hersteller Artikelnummer: HY-181088
• Alternativnummer: MCE-HY-181088-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

PDE3/4-IN-4 is an orally active PDE3A and PDE4B inhibitor with IC50 values of 10 nM and 9.4 nM, respectively. PDE3/4-IN-4 shows selective activity relative to most other PDE family members. PDE3/4-IN-4 modulates the cAMP/PKA/CREB signaling pathway. PDE3/4-IN-4 inhibits pro-inflammatory factor IL-6. PDE3/4-IN-4 reduces expression of inflammatory markers in liver tissue. PDE3/4-IN-4 attenuates liver fibrosis. PDE3/4-IN-4 limits liver damage in cholestatic and sepsis-induced liver disease mice models. PDE3/4-IN-4 can be used for the research of liver injury, cholestatic liver diseases, sepsis-induced liver injury[1].

Produkteigenschaften

• Molekulargewicht: 559.56
• CAS Nummer: [3088024-27-2]
• Formel: C30H27F2N5O4
• Target-Kategorie: Interleukin Related,Phosphodiesterase (PDE)

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound