PDE3/4-IN-4, CAS [[3088024-27-2]] Preis auf Anfrage

Product Overview

• Article Name: PDE3/4-IN-4, CAS [[3088024-27-2]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-181088
• Supplier Catalog Number: HY-181088
• Alternative Catalog Number: MCE-HY-181088-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

PDE3/4-IN-4 is an orally active PDE3A and PDE4B inhibitor with IC50 values of 10 nM and 9.4 nM, respectively. PDE3/4-IN-4 shows selective activity relative to most other PDE family members. PDE3/4-IN-4 modulates the cAMP/PKA/CREB signaling pathway. PDE3/4-IN-4 inhibits pro-inflammatory factor IL-6. PDE3/4-IN-4 reduces expression of inflammatory markers in liver tissue. PDE3/4-IN-4 attenuates liver fibrosis. PDE3/4-IN-4 limits liver damage in cholestatic and sepsis-induced liver disease mice models. PDE3/4-IN-4 can be used for the research of liver injury, cholestatic liver diseases, sepsis-induced liver injury[1].

Product Properties

• Molecular Weight: 559.56
• CAS Number: [3088024-27-2]
• Formula: C30H27F2N5O4
• Target: Interleukin Related,Phosphodiesterase (PDE)

Application Notes

• Application Notes: MCE Product type: Reference compound