G194-0712 is a selective histone deacetylase 5 (HDAC5) activator with an EC50 of 7.96 µM and a Kd of 2.53 µM. G194-0712 restores ACTN4-K417 deacetylation and nuclear import, and increases CSTA expression. G194-0712 accelerates wound closure in chronic wound models, reducing wound area and epithelial gap. G194-0712 can be used for the research of chronic skin wounds, such as diabetic wounds, ischemic wounds, radiation injury wounds[1].
Molekulargewicht:
353.85
CAS Nummer:
[1029737-28-7]
Formel:
C20H20ClN3O
Target-Kategorie:
HDAC
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
