PROTAC SARS-CoV-2 Mpro degrader-7 Preis auf Anfrage

Produktübersicht

• Artikelname: PROTAC SARS-CoV-2 Mpro degrader-7 Preis auf Anfrage
• Artikelnummer: MCE-HY-181193
• Hersteller Artikelnummer: HY-181193
• Alternativnummer: MCE-HY-181193-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: sars-cov-2

Produktbeschreibung

PROTAC SARS-CoV-2 Mpro degrader-7 is a SARS-CoV-2 main protease (Mpro) PROTAC degrader with a DC50 of 0.985 µM. PROTAC SARS-CoV-2 Mpro degrader-7 promotes K48-linked polyubiquitination of SARS-CoV-2 Mpro, leading to proteasome-dependent degradation via the ubiquitin-proteasome system.PROTAC SARS-CoV-2 Mpro degrader-7 forms a ternary complex with SARS-CoV-2 Mpro and CRBN E3 ubiquitin ligase to enable viral protease ubiquitination.PROTAC SARS-CoV-2 Mpro degrader-7 exhibits a high selectivity index, and induces dose-dependent degradation of SARS-CoV-2 Mpro in stable cells expressing the viral protease.PROTAC SARS-CoV-2 Mpro degrader-7 can be used for the research of COVID-19[1].

Produkteigenschaften

• Molekulargewicht: 661.74
• Formel: C35H43N5O8
• Target-Kategorie: PROTACs,SARS-CoV,Virus Protease

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound