PROTAC SARS-CoV-2 Mpro degrader-7 Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-181193
Supplier Catalog Number:
HY-181193
Alternative Catalog Number:
MCE-HY-181193-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alternative Names:
sars-cov-2
PROTAC SARS-CoV-2 Mpro degrader-7 is a SARS-CoV-2 main protease (Mpro) PROTAC degrader with a DC50 of 0.985 µM. PROTAC SARS-CoV-2 Mpro degrader-7 promotes K48-linked polyubiquitination of SARS-CoV-2 Mpro, leading to proteasome-dependent degradation via the ubiquitin-proteasome system.PROTAC SARS-CoV-2 Mpro degrader-7 forms a ternary complex with SARS-CoV-2 Mpro and CRBN E3 ubiquitin ligase to enable viral protease ubiquitination.PROTAC SARS-CoV-2 Mpro degrader-7 exhibits a high selectivity index, and induces dose-dependent degradation of SARS-CoV-2 Mpro in stable cells expressing the viral protease.PROTAC SARS-CoV-2 Mpro degrader-7 can be used for the research of COVID-19[1].
Molecular Weight:
661.74
Formula:
C35H43N5O8
Target:
PROTACs,SARS-CoV,Virus Protease
Application Notes:
MCE Product type: Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted
