PARP1-IN-55, CAS [[3109617-69-5]] Preis auf Anfrage
Artikelnummer:
MCE-HY-181459
Hersteller Artikelnummer:
HY-181459
Alternativnummer:
MCE-HY-181459-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
PARP1-IN-55 is a potent and selective PARP1 inhibitor with an IC50 value of 0.019 µM. PARP1-IN-55 exhibits anti-proliferative selective activity against MCF-7 breast cancer cells (IC50 = 3.6 µM). PARP1-IN-55 inhibits the PARP1-mediated DNA damage repair pathway, induces ROS accumulation, disrupts mitochondrial membrane potential, induced apoptosis and suppresses cancer cell migration, invasion, and colony formation. PARP1-IN-55 can be used for the study of breast cancer[1].
Molekulargewicht:
429.55
CAS Nummer:
[3109617-69-5]
Formel:
C25H35NO5
Target-Kategorie:
Apoptosis,DNA/RNA Synthesis,PARP,Reactive Oxygen Species (ROS)
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
