PARP1-IN-55, CAS [[3109617-69-5]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-181459
Supplier Catalog Number:
HY-181459
Alternative Catalog Number:
MCE-HY-181459-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
PARP1-IN-55 is a potent and selective PARP1 inhibitor with an IC50 value of 0.019 µM. PARP1-IN-55 exhibits anti-proliferative selective activity against MCF-7 breast cancer cells (IC50 = 3.6 µM). PARP1-IN-55 inhibits the PARP1-mediated DNA damage repair pathway, induces ROS accumulation, disrupts mitochondrial membrane potential, induced apoptosis and suppresses cancer cell migration, invasion, and colony formation. PARP1-IN-55 can be used for the study of breast cancer[1].
Molecular Weight:
429.55
CAS Number:
[3109617-69-5]
Formula:
C25H35NO5
Target:
Apoptosis,DNA/RNA Synthesis,PARP,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound
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