ERK5-IN-7 Preis auf Anfrage

Produktübersicht

• Artikelname: ERK5-IN-7 Preis auf Anfrage
• Artikelnummer: MCE-HY-181477
• Hersteller Artikelnummer: HY-181477
• Alternativnummer: MCE-HY-181477-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

ERK5-IN-7 is an orally active ERK5 inhibitor with an IC50 of 403.4 nM. ERK5-IN-7 directly inhibits ERK5 kinase activity, and downregulates the phosphorylation level and total protein expression of ERK5. ERK5-IN-7 induces Apoptosis (upregulates Bax, downregulates Bcl-2, and induces Caspase-3 cleavage). ERK5-IN-7 induces ROS accumulation. ERK5-IN-7 exhibits anticancer effects against Lewis lung cancer[1].

Produkteigenschaften

• Molekulargewicht: 373.24
• Formel: C18H14Cl2N4O
• Target-Kategorie: Apoptosis,Bcl-2 Family,Caspase,ERK,Reactive Oxygen Species (ROS)

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound