TC8026 is an allosteric-covalent inhibitor targeting protein disulfide isomerase (PDI), with an IC50 of 7 µM against human PDI. TC8026 induces endoplasmic reticulum stress-mediated cell apoptosis (apoptosis). TC8026 is a hit compound with PDI inhibitory activity identified via high-throughput screening, and it can be used for the research of glioblastoma[1].
Molekulargewicht:
289.72
Formel:
C14H12ClN3O2
Target-Kategorie:
Apoptosis,PDI
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
