TC8026 is an allosteric-covalent inhibitor targeting protein disulfide isomerase (PDI), with an IC50 of 7 µM against human PDI. TC8026 induces endoplasmic reticulum stress-mediated cell apoptosis (apoptosis). TC8026 is a hit compound with PDI inhibitory activity identified via high-throughput screening, and it can be used for the research of glioblastoma[1].
Molecular Weight:
289.72
Formula:
C14H12ClN3O2
Target:
Apoptosis,PDI
Application Notes:
MCE Product type: Reference compound
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