Poltheta-IN-10, CAS [[3068829-46-6]] Preis auf Anfrage

Produktübersicht

• Artikelname: Poltheta-IN-10, CAS [[3068829-46-6]] Preis auf Anfrage
• Artikelnummer: MCE-HY-181611
• Hersteller Artikelnummer: HY-181611
• Alternativnummer: MCE-HY-181611-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

Poltheta-IN-10 is a Poltheta-pol inhibitor (with a human IC50 of 1.3 nM) that exhibits oral bioavailability in mice and rats. Poltheta-IN-10 binds to the allosteric site of Poltheta-pol, disrupts the microhomology-mediated end-joining DNA repair pathway, and inhibits CYP2C9 (IC50=1.63 µM). Poltheta-IN-10 selectively inhibits the proliferation of HR-deficient cancer cells and induces apoptosis. Poltheta-IN-10 is applicable to the research of HR-deficient cancers[1].

Produkteigenschaften

• Molekulargewicht: 556.51
• CAS Nummer: [3068829-46-6]
• Formel: C27H24F4N6O3
• Target-Kategorie: Apoptosis,Cytochrome P450,DNA/RNA Synthesis

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound