PDE4-IN-34, CAS [[3052591-16-6]] Preis auf Anfrage

Produktübersicht

• Artikelname: PDE4-IN-34, CAS [[3052591-16-6]] Preis auf Anfrage
• Artikelnummer: MCE-HY-181646
• Hersteller Artikelnummer: HY-181646
• Alternativnummer: MCE-HY-181646-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

PDE4-IN-34 is a phosphodiesterase 4 (PDE4) inhibitor, with IC50 values of 19 pM and 14 pM against PDE4B1 and PDE4D2, respectively. PDE4-IN-34 shows weak inhibitory activity against PDE8A1, with an IC50 value of 4.092 µM, and exhibits significant selectivity over other subtypes (IC50 > 10 µM). PDE4-IN-34 improves pulmonary function, reduces inflammatory responses and alleviates lung tissue damage in a rat model induced by cigarette smoke combined with LPS (HY-D1056). PDE4-IN-34 can be used for research related to chronic obstructive pulmonary disease[1].

Produkteigenschaften

• Molekulargewicht: 381.64
• CAS Nummer: [3052591-16-6]
• Formel: C17H11Cl3N2O2
• Target-Kategorie: Phosphodiesterase (PDE),TNF Receptor

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound