PDE4-IN-34, CAS [[3052591-16-6]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-181646
Supplier Catalog Number:
HY-181646
Alternative Catalog Number:
MCE-HY-181646-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
PDE4-IN-34 is a phosphodiesterase 4 (PDE4) inhibitor, with IC50 values of 19 pM and 14 pM against PDE4B1 and PDE4D2, respectively. PDE4-IN-34 shows weak inhibitory activity against PDE8A1, with an IC50 value of 4.092 µM, and exhibits significant selectivity over other subtypes (IC50 > 10 µM). PDE4-IN-34 improves pulmonary function, reduces inflammatory responses and alleviates lung tissue damage in a rat model induced by cigarette smoke combined with LPS (HY-D1056). PDE4-IN-34 can be used for research related to chronic obstructive pulmonary disease[1].
Molecular Weight:
381.64
CAS Number:
[3052591-16-6]
Formula:
C17H11Cl3N2O2
Target:
Phosphodiesterase (PDE),TNF Receptor
Application Notes:
MCE Product type: Reference compound
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