EGFR-IN-200, CAS [[3102899-89-5]] Preis auf Anfrage

Produktübersicht

• Artikelname: EGFR-IN-200, CAS [[3102899-89-5]] Preis auf Anfrage
• Artikelnummer: MCE-HY-181657
• Hersteller Artikelnummer: HY-181657
• Alternativnummer: MCE-HY-181657-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

EGFR-IN-200 is an inhibitor targeting EGFR, TNF-alpha, and the IL-6/GP130 complex, which potently targets human EGFR (IC50=0.03 µM), TNF-alpha (IC50=3.1 µM), and the IL-6/GP130 complex (IC50=1.6 µM). EGFR-IN-200 binds to the ATP pocket of EGFR, the trimer interface of TNF-alpha, and the cytokine-receptor interface of IL-6/GP130, induces G2/M cell cycle arrest, apoptosis, and antiproliferative activity. EGFR-IN-200 exhibits high gastrointestinal absorbability, low BBB permeability, and complies with the Lipinskis rule. EGFR-IN-200 can be used for the research of lung cancer and breast adenocarcinoma[1].

Produkteigenschaften

• Molekulargewicht: 499.94
• CAS Nummer: [3102899-89-5]
• Formel: C28H22ClN3O4
• Target-Kategorie: Apoptosis,EGFR,Interleukin Related,TNF Receptor

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound