IKKbeta-IN-7, CAS [[3117527-92-8]] Preis auf Anfrage

Produktübersicht

• Artikelname: IKKbeta-IN-7, CAS [[3117527-92-8]] Preis auf Anfrage
• Artikelnummer: MCE-HY-181837
• Hersteller Artikelnummer: HY-181837
• Alternativnummer: MCE-HY-181837-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

IKKbeta-IN-7 is an IKKbeta inhibitor with an IC50 value of 9.44 µM. IKKbeta-IN-7 induces DNA damage, S-phase cell cycle arrest, ROS accumulation, mitochondrial membrane potential loss, and apoptosis. IKKbeta-IN-7 inhibits phosphorylation of p65 and IkappaBalpha, suppresses p65 nuclear translocation, and regulates NF-kappaB-controlled genes. IKKbeta-IN-7 suppresses tumor growth in xenograft models and shows activity against colorectal cancer with low normal cell cytotoxicity. IKKbeta-IN-7 can be used for the research of colorectal cancer[1].

Produkteigenschaften

• Molekulargewicht: 786.82
• CAS Nummer: [3117527-92-8]
• Formel: C45H42N2O11
• Target-Kategorie: Apoptosis,Bcl-2 Family,IKK,NF-kappaB,Reactive Oxygen Species (ROS)

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound