IKKbeta-IN-7, CAS [[3117527-92-8]] Preis auf Anfrage

Product Overview

• Article Name: IKKbeta-IN-7, CAS [[3117527-92-8]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-181837
• Supplier Catalog Number: HY-181837
• Alternative Catalog Number: MCE-HY-181837-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

IKKbeta-IN-7 is an IKKbeta inhibitor with an IC50 value of 9.44 µM. IKKbeta-IN-7 induces DNA damage, S-phase cell cycle arrest, ROS accumulation, mitochondrial membrane potential loss, and apoptosis. IKKbeta-IN-7 inhibits phosphorylation of p65 and IkappaBalpha, suppresses p65 nuclear translocation, and regulates NF-kappaB-controlled genes. IKKbeta-IN-7 suppresses tumor growth in xenograft models and shows activity against colorectal cancer with low normal cell cytotoxicity. IKKbeta-IN-7 can be used for the research of colorectal cancer[1].

Product Properties

• Molecular Weight: 786.82
• CAS Number: [3117527-92-8]
• Formula: C45H42N2O11
• Target: Apoptosis,Bcl-2 Family,IKK,NF-kappaB,Reactive Oxygen Species (ROS)

Application Notes

• Application Notes: MCE Product type: Reference compound