Telomeric G4s ligand 2, CAS [[3094716-52-3]]

Produktübersicht

• Artikelname: Telomeric G4s ligand 2, CAS [[3094716-52-3]]
• Artikelnummer: MCE-HY-181850
• Hersteller Artikelnummer: HY-181850
• Alternativnummer: MCE-HY-181850-50MG,MCE-HY-181850-5MG,MCE-HY-181850-100MG,MCE-HY-181850-10MG,MCE-HY-181850-25MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

Telomeric G4s ligand 2 is an orally active, selective ligand of telomeric G-quadruplex (G4), with an IC50 of 0.4 µM. Telomeric G4s ligand 2 binds to dimeric telomeric G4, inhibits the activities of DHX36 and BLM helicases. Telomeric G4s ligand 2 activates cGAS-STING and TERRA-ZBP1 pathways, inducing autophagy and G2/M cell cycle arrest, and exhibits antiproliferative effects across cancer cell lines. Telomeric G4s ligand 2 can be used for the study of colorectal cancer[1].

Produkteigenschaften

• Molekulargewicht: 432.56
• CAS Nummer: [3094716-52-3]
• Formel: C25H32N6O
• Target-Kategorie: Autophagy,Cyclic GMP-AMP Synthase,DNA/RNA Synthesis,G-quadruplex,STING

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound