PROTAC BET Degrader-16, CAS [[2410947-65-6]] Preis auf Anfrage

Produktübersicht

• Artikelname: PROTAC BET Degrader-16, CAS [[2410947-65-6]] Preis auf Anfrage
• Artikelnummer: MCE-HY-181867
• Hersteller Artikelnummer: HY-181867
• Alternativnummer: MCE-HY-181867-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

PROTAC BET Degrader-16 (Compound A10) is a BET PROTAC degrader with a DC50 of 0.31 nM against BRD4, and it preferentially targets BRD4 over other BET family members. PROTAC BET Degrader-16 degrades BRD2, BRD3 and BRD4 via the ubiquitin-proteasome system, a process that requires target binding and recruitment of the CRBN E3 ligase. PROTAC BET Degrader-16 induces cell cycle arrest and promotes apoptosis. PROTAC BET Degrader-16 exerts anti-tumor activity against acute myeloid leukemia[1].

Produkteigenschaften

• Molekulargewicht: 885.93
• CAS Nummer: [2410947-65-6]
• Formel: C44H45F2N7O9S
• Target-Kategorie: Apoptosis,Epigenetic Reader Domain,PROTACs

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound