PROTAC BET Degrader-16, CAS [[2410947-65-6]] Preis auf Anfrage

Product Overview

• Article Name: PROTAC BET Degrader-16, CAS [[2410947-65-6]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-181867
• Supplier Catalog Number: HY-181867
• Alternative Catalog Number: MCE-HY-181867-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

PROTAC BET Degrader-16 (Compound A10) is a BET PROTAC degrader with a DC50 of 0.31 nM against BRD4, and it preferentially targets BRD4 over other BET family members. PROTAC BET Degrader-16 degrades BRD2, BRD3 and BRD4 via the ubiquitin-proteasome system, a process that requires target binding and recruitment of the CRBN E3 ligase. PROTAC BET Degrader-16 induces cell cycle arrest and promotes apoptosis. PROTAC BET Degrader-16 exerts anti-tumor activity against acute myeloid leukemia[1].

Product Properties

• Molecular Weight: 885.93
• CAS Number: [2410947-65-6]
• Formula: C44H45F2N7O9S
• Target: Apoptosis,Epigenetic Reader Domain,PROTACs

Application Notes

• Application Notes: MCE Product type: Reference compound