Lenalidomide-CO-C7-NH2, CAS [[1957236-16-6]] Preis auf Anfrage

Produktübersicht

• Artikelname: Lenalidomide-CO-C7-NH2, CAS [[1957236-16-6]] Preis auf Anfrage
• Artikelnummer: MCE-HY-181868
• Hersteller Artikelnummer: HY-181868
• Alternativnummer: MCE-HY-181868-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

Lenalidomide-CO-C7-NH2 is a CRBN-dependent intermediate of BET PROTAC degrader. Consisting of the E3 ubiquitin ligase ligand Lenalidomide (HY-A0003) conjugated with a PROTAC linker, Lenalidomide-CO-C7-NH2 induces the specific degradation of the oncoprotein BRD4. By depleting BRD4, Lenalidomide-CO-C7-NH2 effectively inhibits cancer cell proliferation, induces cell cycle arrest and promotes apoptosis, thereby exhibiting significant anti-tumor activity in xenograft models. Lenalidomide-CO-C7-NH2 serves as an important tool molecule for the study of acute myeloid leukemia[1].

Produkteigenschaften

• Molekulargewicht: 400.47
• CAS Nummer: [1957236-16-6]
• Formel: C21H28N4O4
• Target-Kategorie: E3 Ligase Ligand-Linker Conjugates

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound