Lenalidomide-CO-C7-NH2, CAS [[1957236-16-6]] Preis auf Anfrage

Product Overview

• Article Name: Lenalidomide-CO-C7-NH2, CAS [[1957236-16-6]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-181868
• Supplier Catalog Number: HY-181868
• Alternative Catalog Number: MCE-HY-181868-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

Lenalidomide-CO-C7-NH2 is a CRBN-dependent intermediate of BET PROTAC degrader. Consisting of the E3 ubiquitin ligase ligand Lenalidomide (HY-A0003) conjugated with a PROTAC linker, Lenalidomide-CO-C7-NH2 induces the specific degradation of the oncoprotein BRD4. By depleting BRD4, Lenalidomide-CO-C7-NH2 effectively inhibits cancer cell proliferation, induces cell cycle arrest and promotes apoptosis, thereby exhibiting significant anti-tumor activity in xenograft models. Lenalidomide-CO-C7-NH2 serves as an important tool molecule for the study of acute myeloid leukemia[1].

Product Properties

• Molecular Weight: 400.47
• CAS Number: [1957236-16-6]
• Formula: C21H28N4O4
• Target: E3 Ligase Ligand-Linker Conjugates

Application Notes

• Application Notes: MCE Product type: Reference compound