STIM1-TFR1-IN-1, CAS [[2196106-61-1]] Preis auf Anfrage

Produktübersicht

• Artikelname: STIM1-TFR1-IN-1, CAS [[2196106-61-1]] Preis auf Anfrage
• Artikelnummer: MCE-HY-181953
• Hersteller Artikelnummer: HY-181953
• Alternativnummer: MCE-HY-181953-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

STIM1-TFR1-IN-1 is a stromal interaction molecule 1 (STIM1)-transferrin receptor 1 (TFR1) protein complex inhibitor with a Kd of 2.18 µM for STIM1-CD protein. STIM1-TFR1-IN-1 blocks STIM1-TFR1 interaction and reduce TFR1-mediated iron uptake activity. STIM1-TFR1-IN-1 inhibits ferroptosis, lipid peroxidation and ROS production, enhances glutathione peroxidase 4 (GPX4) activity and glutathione/oxidized glutathione ratio, and rescues ferroptosis-associated mitochondrial morphological changes. STIM1-TFR1-IN-1 exhibits neuroprotectiveeffects and reduces brain injury. STIM1-TFR1-IN-1 can be used for the research of intracerebral hemorrhage[1].

Produkteigenschaften

• Molekulargewicht: 319.43
• CAS Nummer: [2196106-61-1]
• Formel: C15H21N5OS
• Target-Kategorie: Ferroptosis,Glutathione Peroxidase,Reactive Oxygen Species (ROS),Transferrin Receptor

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound