STIM1-TFR1-IN-1, CAS [[2196106-61-1]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-181953
Supplier Catalog Number:
HY-181953
Alternative Catalog Number:
MCE-HY-181953-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
STIM1-TFR1-IN-1 is a stromal interaction molecule 1 (STIM1)-transferrin receptor 1 (TFR1) protein complex inhibitor with a Kd of 2.18 µM for STIM1-CD protein. STIM1-TFR1-IN-1 blocks STIM1-TFR1 interaction and reduce TFR1-mediated iron uptake activity. STIM1-TFR1-IN-1 inhibits ferroptosis, lipid peroxidation and ROS production, enhances glutathione peroxidase 4 (GPX4) activity and glutathione/oxidized glutathione ratio, and rescues ferroptosis-associated mitochondrial morphological changes. STIM1-TFR1-IN-1 exhibits neuroprotectiveeffects and reduces brain injury. STIM1-TFR1-IN-1 can be used for the research of intracerebral hemorrhage[1].
Molecular Weight:
319.43
CAS Number:
[2196106-61-1]
Formula:
C15H21N5OS
Target:
Ferroptosis,Glutathione Peroxidase,Reactive Oxygen Species (ROS),Transferrin Receptor
Application Notes:
MCE Product type: Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted
