KRAS G12C-IN-78, CAS [[3023465-20-2]] Preis auf Anfrage

Produktübersicht

• Artikelname: KRAS G12C-IN-78, CAS [[3023465-20-2]] Preis auf Anfrage
• Artikelnummer: MCE-HY-181965
• Hersteller Artikelnummer: HY-181965
• Alternativnummer: MCE-HY-181965-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

KRAS G12C-IN-78 is a selective SWII-binding KRASG12C dual inhibitor targeting both inactive and active states. KRAS G12C-IN-78 rapidly inhibits ERK1/2 phosphorylation, induces covalent adduct formation with endogenous KRASG12C, suppresses MAPK pathway gene expression, and inhibits cellular proliferation in KRASG12C mutant cells. KRAS G12C-IN-78 can be used for the research of KRASG12C mutant solid tumors, including pancreatic ductal adenocarcinoma and non-small cell lung cancer[1].

Produkteigenschaften

• Molekulargewicht: 729.75
• CAS Nummer: [3023465-20-2]
• Formel: C37H31F4N7O3S
• Target-Kategorie: ERK,p38 MAPK,Ras

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound