Atopaxar (hydrochloride), CAS [[474544-83-7]] Preis auf Anfrage

Produktübersicht

• Artikelname: Atopaxar (hydrochloride), CAS [[474544-83-7]] Preis auf Anfrage
• Artikelnummer: MCE-HY-18200A
• Hersteller Artikelnummer: HY-18200A
• Alternativnummer: MCE-HY-18200A-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: E5555 (hydrochloride), ER-172594-00 (hydrochloride)

Produktbeschreibung

Atopaxar hydrochloride (E5555 hydrochloride) is the hydrochloride salt form of Atopaxar (HY-18200). Atopaxar hydrochloride is an orally active, selective and reversible antagonist for thrombin receptor protease-activated receptor-1 (PAR-1). Atopaxar hydrochloride is the inhibitor for Janus kinase 1 (JAK1) and JAK2, which inhibits the JAK-STAT with EC50 of 5.90 µM in A549. Atopaxar hydrochloride inhibits the cell viability of A549 (IC50=7.02 µM), arrests the cell cycle at G1 phase and induces apoptosis. Atopaxar hydrochloride exhibits antiplatelet and antitumor activities. Atopaxar hydrochloride can be used for the research of atherothrombotic disease[1][2][3].

Produkteigenschaften

• Molekulargewicht: 564.09
• CAS Nummer: [474544-83-7]
• Formel: C29H39ClFN3O5
• Target-Kategorie: Apoptosis,JAK,Protease Activated Receptor (PAR)

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound