FXR agonist 17, CAS [[3107769-23-0]] Preis auf Anfrage

Produktübersicht

• Artikelname: FXR agonist 17, CAS [[3107769-23-0]] Preis auf Anfrage
• Artikelnummer: MCE-HY-182026
• Hersteller Artikelnummer: HY-182026
• Alternativnummer: MCE-HY-182026-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

FXR agonist 17 is an orally active, steroidal FXR agonist with EC50 values of 42.2 nM (TR-FRET) and 176.4 nM (luciferase reporter assay), respectively. FXR agonist 17 activates TGR5 (EC50 = 2.6 µM) but does not activate hMRGPRX4. FXR agonist 17 exerts anti-inflammatory, hepatoprotective and antifibrotic effects, improves the non-alcoholic steatohepatitis (NAFLD) activity score and reduces the severity of liver fibrosis. FXR agonist 17 can be used for the research of NAFLD, cholestatic liver disease and liver fibrosis[1].

Produkteigenschaften

• Molekulargewicht: 502.75
• CAS Nummer: [3107769-23-0]
• Formel: C29H46N2O3S
• Target-Kategorie: FXR,G protein-coupled Bile Acid Receptor 1,Reactive Oxygen Species (ROS),TNF Receptor

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound