TGF-beta1/Smad3-IN-2 is an orally effective antifibrotic agent. TGF-beta1/Smad3-IN-2 has high affinity for VDR and can inhibit the TGFbeta/SMAD3 signaling pathway. TGF-beta1/Smad3-IN-2 inhibits hepatic stellate cell activation, reduces extracellular matrix deposition, and alleviates liver fibrosis in a bile duct ligation mouse model. TGF-beta1/Smad3-IN-2 can be used for the research of liver fibrosis[1].
Molekulargewicht:
565.78
Formel:
C38H47NO3
Target-Kategorie:
TGF-beta/Smad,VD/VDR
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
