GSTP1-IN-1 is a selective GSTP1 inhibitor with an IC50 of 0.79 µM and a Kd of 0.63 µM. GSTP1-IN-1 inhibits the proliferation of gastric cancer cells, induces ROS production and depletes glutathione. GSTP1-IN-1 achieves systemic exposure and is well tolerated in xenograft mouse models, while inhibiting tumor growth. GSTP1-IN-1 can be used in gastric cancer-related research[1].
Molekulargewicht:
687.65
Formel:
C30H28F3N7O7S
Target-Kategorie:
Glutathione S-transferase,Reactive Oxygen Species (ROS)
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
