GSTP1-IN-1 is a selective GSTP1 inhibitor with an IC50 of 0.79 µM and a Kd of 0.63 µM. GSTP1-IN-1 inhibits the proliferation of gastric cancer cells, induces ROS production and depletes glutathione. GSTP1-IN-1 achieves systemic exposure and is well tolerated in xenograft mouse models, while inhibiting tumor growth. GSTP1-IN-1 can be used in gastric cancer-related research[1].
Molecular Weight:
687.65
Formula:
C30H28F3N7O7S
Target:
Glutathione S-transferase,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound
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