GSK-1264 is an HIV-1 integrase inhibitor.GSK-1264 binds to a site spanning the HIV-1 integrase catalytic core domain and C-terminal domain, mediates formation of an open polymer of HIV-1 integrase dimers via inhibitor-bridged contacts between adjacent dimers.GSK-1264 disrupts late-stage HIV replication by interfering with viral particle assembly.GSK-1264 stimulates inappropriate polymerization of HIV-1 integrase.GSK-1264 can be used for the research of HIV infection[1].
Molekulargewicht:
453.50
CAS Nummer:
[1392118-63-6]
Formel:
C26H28FNO5
Target-Kategorie:
HIV Integrase
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
