GSK-1264 is an HIV-1 integrase inhibitor.GSK-1264 binds to a site spanning the HIV-1 integrase catalytic core domain and C-terminal domain, mediates formation of an open polymer of HIV-1 integrase dimers via inhibitor-bridged contacts between adjacent dimers.GSK-1264 disrupts late-stage HIV replication by interfering with viral particle assembly.GSK-1264 stimulates inappropriate polymerization of HIV-1 integrase.GSK-1264 can be used for the research of HIV infection[1].
Molecular Weight:
453.50
CAS Number:
[1392118-63-6]
Formula:
C26H28FNO5
Target:
HIV Integrase
Application Notes:
MCE Product type: Reference compound
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