Carboxyatractyloside, CAS [[35988-42-2]] Preis auf Anfrage

Produktübersicht

• Artikelname: Carboxyatractyloside, CAS [[35988-42-2]] Preis auf Anfrage
• Artikelnummer: MCE-HY-182303
• Hersteller Artikelnummer: HY-182303
• Alternativnummer: MCE-HY-182303-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: CATR

Produktbeschreibung

Carboxyatractyloside (CATR) is a tight-binding inhibitor of adenine nucleotide translocase, and represents the major toxic component of Xanthium sibiricum. Carboxyatractyloside competes with ADP for binding to the translocase, blocks the translocation of ADP/ATP across the inner mitochondrial membrane, and thereby inhibits ADP-stimulated respiration. In the presence of Cyclosporin A (HY-B0579), Carboxyatractyloside still induces permeability transition in liver mitochondria of aged rats, exhibiting significant hepatotoxicity and nephrotoxicity. Carboxyatractyloside is widely used in studies related to hepatotoxicity, nephrotoxicity and Alzheimers disease[1][2][3].

Produkteigenschaften

• Molekulargewicht: 770.82
• CAS Nummer: [35988-42-2]
• Formel: C31H46O18S2
• Target-Kategorie: Methionine Adenosyltransferase (MAT)

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound