Carboxyatractyloside, CAS [[35988-42-2]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-182303
Supplier Catalog Number:
HY-182303
Alternative Catalog Number:
MCE-HY-182303-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alternative Names:
CATR
Carboxyatractyloside (CATR) is a tight-binding inhibitor of adenine nucleotide translocase, and represents the major toxic component of Xanthium sibiricum. Carboxyatractyloside competes with ADP for binding to the translocase, blocks the translocation of ADP/ATP across the inner mitochondrial membrane, and thereby inhibits ADP-stimulated respiration. In the presence of Cyclosporin A (HY-B0579), Carboxyatractyloside still induces permeability transition in liver mitochondria of aged rats, exhibiting significant hepatotoxicity and nephrotoxicity. Carboxyatractyloside is widely used in studies related to hepatotoxicity, nephrotoxicity and Alzheimers disease[1][2][3].
Molecular Weight:
770.82
CAS Number:
[35988-42-2]
Formula:
C31H46O18S2
Target:
Methionine Adenosyltransferase (MAT)
Application Notes:
MCE Product type: Reference compound
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