Bax activator-2, CAS [[3034297-25-8]] Preis auf Anfrage

Produktübersicht

• Artikelname: Bax activator-2, CAS [[3034297-25-8]] Preis auf Anfrage
• Artikelnummer: MCE-HY-182349
• Hersteller Artikelnummer: HY-182349
• Alternativnummer: MCE-HY-182349-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

Bax activator-2 (compound 27c) is a pro-apoptotic agent targeting BAX, with an IC50 of 0.30 µmol/L against human BAX. Bax activator-2 binds to the trigger site of BAX and induces its conformational change. Bax activator-2 induces mitochondrial depolarization, cytochrome c release, caspase-3/9 cleavage and PARP cleavage, thereby initiating apoptosis. Bax activator-2 exhibits cytotoxicity against various cancer cell lines, shows reduced cytotoxicity in BAX-knockout A549 cells, and has low cytotoxicity against non-cancerous cell lines. Bax activator-2 can be used in studies related to acute myeloid leukemia and solid tumors[1].

Produkteigenschaften

• Molekulargewicht: 505.52
• CAS Nummer: [3034297-25-8]
• Formel: C30H23N3O5
• Target-Kategorie: Bcl-2 Family

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound